Application of Liquid Nitrogen in Different Fields (2) Biomedical Field

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Liquid nitrogen: Nitrogen gas in the liquid state. Inert, colorless, odorless, non-corrosive, non-flammable, extremely cryogenic temperature. Nitrogen forms the majority of the atmosphere (78.03% by volume and 75.5% by weight).Nitrogen is inactive and does not support combustion. Frostbite caused by excessive endothermic contact during vaporization.

Liquid nitrogen is a convenient cold source. Due to its unique properties, liquid nitrogen has been gradually paid more and more attention and recognized by people. It has been more and more widely used in animal husbandry, medical industry, food industry, and cryogenic research fields. In electronics, metallurgy, aerospace, machinery manufacturing and other aspects of the application has been expanding and developing.

Liquid nitrogen cryogenic microbial collection skills

The principle of liquid nitrogen permanent collection method, which collects bacteria species at -196℃, is to collect microorganisms effectively by taking advantage of the tendency to stop metabolism of microorganisms below -130℃.Macrofungi are an important group of fungi (fungi that form large fruiting bodies in fungi, generally referring to mushroom or mushroom in a broad sense). Many species have high nutritional costs and medicinal costs, and they have a promising application prospect among fungi. In addition, some large fungi can roughly analyze dead plants, which play an important role in maintaining natural material circulation and ecological balance, and can be developed and applied to paper industry and environmental purification. Some large fungi can cause tree diseases or damage a variety of wood products. The enhancement of the understanding of these pathogenic fungi is conducive to the prevention and elimination of harm. The exemplar collection of macrofungi is of great significance to the quiet and collection of microbial species resources, the permanent and useful collection of genetic resources, and the sharing of biodiversity in different places

Genetic survival of agricultural organisms

Shanghai has invested more than 41 million yuan to set up and deploy a comprehensive database of agricultural biological genes in China. The seed industry, which has the potential to open up a global market, will use the gene bank as a source of breeding materials, the agricultural industry said. The Shanghai Agricultural Biological gene Bank, with a total area of 3,300 square meters, will be located in the Shanghai Academy of Agricultural Sciences. It will collect five kinds of agricultural biological genetic resources including plant seeds, plant extracellular materials, animal reproductive cells, microbial strains and plant genetic engineering materials.

Cold medicine

The rapid development of clinical cryogenic medicine has promoted the development of transplantation medicine, especially in bone marrow, hematopoietic stem cells, skin, cornea, internal excretory glands, blood vessels and valves, etc. Successful hematopoietic stem cell transplantation depends on the survival of hematopoietic stem cells. In the cooling and freezing process of biological samples, during the phase transition from liquid to solid, certain heat will be released and its temperature will rise. The freezing process without controlling the cooling rate will lead to the death of structural cells. The key to improve the survival rate of frozen samples is to correctly determine the phase change point of biological samples and to use microcomputer to cool the pace so as to increase the amount of liquid nitrogen input during the phase change, to suppress the temperature rise of phase change samples and to make the cells pass phase change quietly and quickly.

Clinical medicine

Liquid nitrogen is a widely used refrigerant in cryosurgery. It's a refrigerant that's been invented so far, and when you inject it into a cryogenic medical device, it acts like a scalpel, and you can do any surgery. Cryotherapy is a treatment that uses cryogenic temperature to shatter the lesion structure. As a result of the sharp change in the temperature of the cell, crystal formation in the structure surface, so that the cell dehydration, shrinkage, electrolytes and other changes, freezing can also make local blood flow rate slow, blood stasis or embolism caused by cell hypoxia death.

HL Cryogenic Equipment

HL Cryogenic Equipment which was founded in 1992 is a brand affiliated to HL Cryogenic Equipment Company Cryogenic Equipment Co.,Ltd. HL Cryogenic Equipment is committed to the design and manufacture of the High Vacuum Insulated Cryogenic Piping System and related Support Equipment to meet the various needs of customers. The Vacuum Insulated Pipe and Flexible Hose are constructed in a high vacuum and multi-layer multi-screen special insulated materials, and passes through a series of extremely strict technical treatments and high vacuum treatment, which is used for transferring of liquid oxygen, liquid nitrogen, liquid argon, liquid hydrogen, liquid helium, liquefied ethylene gas LEG and liquefied nature gas LNG.

The product series of Vacuum Valve, Vacuum Pipe, Vacuum Hose and Phase Separator in HL Cryogenic Equipment Company, which passed through a series of extremely strict technical treatments, are used for transporting of liquid oxygen, liquid nitrogen, liquid argon, liquid hydrogen, liquid helium, LEG and LNG, and these products are serviced for cryogenic equipment (e.g. cryogenic tanks and dewar flasks etc.) in industries of electronics, superconductor, chips, MBE, pharmacy, biobank / cellbank, food & beverage, automation assembly, and scientific research etc.

Post time: Nov-24-2021