According to the research results of international authoritative institutions, diseases and senescence of the human body start from cell damage. The ability of cells to regenerate themselves will decline with the increase of age. When aging and diseased cells continue to accumulate, new cells cannot replace them in time, and diseases and senescence inevitably occur.
Stem cells are a special type of cell in the body that can turn into any type of cell in our body, used to repair damage and replace aging cells. In recent years, with the deepening of the concept of stem cell treatment for diseases and anti-aging effect, stem cell cryopreservation has become an important choice for most people's future health.
The Storage Time of Stem Cells in the Liquid Nitrogen System
Theoretically, liquid nitrogen cryopreservation can preserve cell resources indefinitely. At present, the known longest preserved cell sample in the laboratory of the Chinese Academy of Sciences has been stored for 70 years. This does not mean that the frozen storage can only be done for 70 years, but the development of the whole industry only has a history of 70 years. With the development of The Times, the time of frozen stem cells will be continuously extended.
Of course, the duration of cryopreservation ultimately depends on the cryopreservation temperature, as only deep cryopreservation can make cells dormant. Under normal circumstances, it can be stored for 5 hours at room temperature. Low temperature 8 degrees Celsius can be stored for 48 hours. Deep low temperature refrigerators -80 degrees Celsius can be stored for a month. Liquid nitrogen is theoretically permanent at -196 degrees Celsius.
In 2011, the results of in vitro and animal experiments published in Blood by Professor Broxmeyer and his team from Indiana University, which is an expert in the research of cord BLOOD stem cell biology, proved that stem cells stored for 23.5 years could maintain their original potential of in vitro proliferation, differentiation, expansion and in vivo implantation.
In 2018, a stem cell collected in Beijing Obstetrics and Gynecology Hospital was frozen for 20 years and 4 months in June 1998. After resuscitation, the activity was 99.75%!
So far, there are more than 300 cord blood banks in the world, with 40 percent in Europe, 30 percent in North America, 20 percent in Asia and 10 percent in Oceania.
The World Marrow Donor Association (WMDA) was established in 1994 and is based in Leiden, the Netherlands. The largest is the National Marrow Donor Program (NMDP), based in Minneapolis, Minn., and established in 1986.DKMS has about 4 million donors, giving more than 4, 000 each year. Chinese Marrow Donor Program (CMDP), established in 1992, is the fourth largest marrow bank after the United States, Germany and Brazil. They can differentiate into other types of blood cells, such as red blood cells, white blood cells, platelets and so on.
Liquid Nitrogen System for Stem Cell Storage
The stem cell storage system mainly consists of a large liquid nitrogen cryogenic tank, a set of vacuum jacketed piping system (including vacuum jacketed pipe, vacuum jacketed hose, phase separator, vacuum jacketed stop valve, air-liquid barrier, etc.) and a biological container for storing stem cell samples in the tank.
Liquid nitrogen provides continuous low temperature protection in biological containers. Due to the natural gasification of liquid nitrogen, it is usually necessary to fill the biological containers once a week to ensure that the temperature in the biological container is low enough.
HL Cryogenic Equipment
HL Cryogenic Equipment which was founded in 1992 is a brand affiliated to Chengdu Holy Cryogenic Equipment Company in China. HL Cryogenic Equipment is committed to the design and manufacture of the High Vacuum Insulated Cryogenic Piping System and related Support Equipment.
Post time: Jun-03-2021